Comparative in vitro activities of investigational peptide deformylase inhibitor NVP LBM-415 and other agents against human mycoplasmas and ureaplasmas.

نویسندگان

  • Ken B Waites
  • Nipun B Reddy
  • Donna M Crabb
  • Lynn B Duffy
چکیده

Peptide deformylase inhibitor LBM-415 and seven other drugs were tested against Mycoplasma pneumoniae (100 isolates), Mycoplasma hominis (20 isolates), Mycoplasma fermentans (10 isolates), and Ureaplasma species (50 isolates). LBM-415 was active against M. pneumoniae (MICs, <or=0.008 microg/ml). It showed no activity against M. hominis and M. fermentans and modest activity against Ureaplasma spp.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 49 6  شماره 

صفحات  -

تاریخ انتشار 2005